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Postdoctoral position

Published: : 2017-09-27

Uppsala University is an international research university focused on the development of science and education. Our most important assets are all the individuals who with their curiosity and their dedication make Uppsala University one of Sweden’s most exciting work places. Uppsala University has 40,000 students, 7,000 employees and a turnover of SEK 6,5 billion.

The Department of Immunology, Genetics and Pathology at Uppsala University (http://www.igp.uu.se) has a broad research profile with several strong research groups focused on Genomics, Cancer and Molecular Diagnostics. Research is presently conducted in the following areas: Medical and Clinical Genetics, Immunology, Pathology, Tumor Biology and Vascular Biology. Parts of the organization are also integrated with the departments for Clinical Genetics, Immunology and Pathology-Cythology at Akademiska sjukhuset, Uppsala. The department provides a well-developed infrastructure for advanced molecular sciences, including access to front-line technology as well as core facilities for cell analyses, DNA sequencing and genotyping. The Department has a yearly turnover of around 340 million SEK with a staff of around 340 people, 120 of which are PhD-students.

Work description:
We are seeking a postdoc for experimental work in a cross-disciplinary team focused on brain tumor systems biology. This role involves: (1) systematic analysis of targeted interventions in a unique biobank of patient-derived cell cultures, using very large scale (robotic) SMART-SEQ2 and Perturb-Seq. (2) characterization and follow-up of newly identified combinatorial targets and vulnerability genes for treatment of neural tumors, using a broad range of molecular biology techniques, including gene editing. The project aims at a leading contribution towards improved therapies against brain cancer and offers training state-of-the-art cancer systems biology, involving a tight interaction between experimental and computational researchers. In addition to the above research, the role involves participation in a leading cell culture biobanking effort. The position is within a 5-year project with excellent resources and facilities, with responsibilities in terms of several academic tasks, including authoring papers, presenting results, writing proposals and reporting to funding organizations.

Qualifications:

  • Doctoral degree in a relevant area, e.g. biomedicine, biotechnology, pharmacology or medicine
  • Documented advanced experience of molecular biological experimental work, including gene perturbations and cell based assays
  • Documented experience of working in cross-disciplinary teams that bridge molecular biology or cell biology experimental research and bioinformatics
  • Deep knowledge in either of i) cell biology, ii) oncology, iii) pharmacology

Merits:

  • Documented experience of cancer biology, cancer genetics, or neurooncology
  • Documented experience of cancer stem cell models
  • Advanced experience of high-throughput studies, e.g. highly automated drug screening in mammalian cells

Application:
Your application should comprise a CV, copies of degrees and relevant study transcripts and grades, publications and a short description of your research interests. We request that you provide references and preferably provide one or more letters of recommendation. The applications are assessed according to these criteria: basic training, prior experience in related areas, qualifications as above and personal qualities.

Salary: According to individual qualifications

Start date: 2018-01-01 or as soon as possible.

Form of employment: general temporary employment of two years

Extent of employment: 100%

For more information contact:
Associate Professor Sven Nelander, sven.nelander@igp.uu.se, nelanderlab.org

You are welcome to apply no later than Oct 31, 2017. UFV-PA 2017/3197.

We decline offers of recruitment and advertising help. We only accept the application the way described in the advertisement.

Placement: Department of Immunology, Genetics and Pathology

Type of employment: Full time , Temporary position longer than 6 months

Number of positions: 1

Working hours: 100%

Town: Uppsala

County: Uppsala län

Country: Sweden

Union representative: Ellena Papaioannou, Seko
Per Sundman, Saco-rådet
Suzanne Borén Andersson, TCO/ST

Number of reference: UFV-PA 2017/3197

Last application date: 2017-10-31

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