Helge Rask-Andersen
Professor i experimentell otologi vid Institutionen för kirurgiska vetenskaper; Öron-, näs- och halssjukdomar
- Mobiltelefon:
- 070-611 02 67
- E-post:
- helge.rask-andersen@uu.se
- Besöksadress:
- Akademiska sjukhuset, ingång 7879
751 85 Uppsala - Postadress:
- Akademiska sjukhuset, ingång 7879
751 85 Uppsala
- Akademiska meriter:
- MD, docent i öron-, näs- och halssjukdomar
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Kort presentation
Jag är senior professor i experimentell otologi. Jag driver ett forskningslaboratorium på Akademiska sjukhuset. Intresset är främst yrselsjukdomen Meniere och cochleaimplantat. Det senare har revolutionerat behandlingen av gravt hörselskadade samt döva. Vi har ett rikt internationellt samarbete med öronforskare och inom EU när det gäller regeneration och stamceller. Genom kanadensiska forskare samarbetar vi även inom bildrekonstruktion och 3D analys där vi använder synkrotronteknik.
Publikationer
Senaste publikationer
- The ultrastructure of a stria vascularis in the auditory organ of the cuban crocodile (Crocodylus rhombifer) (2023)
- The Acute Effects of Furosemide on Na-K-Cl Cotransporter-1, Fetuin-A and Pigment Epithelium-Derived Factor in the Guinea Pig Cochlea (2022)
- Auditory brainstem implant pitch discrimination and auditory outcome (2022)
- Unlocking the human inner ear for therapeutic intervention (2022)
- Regeneration in the Auditory Organ in Cuban and African Dwarf Crocodiles (Crocodylus rhombifer and Osteolaemus tetraspis) Can We Learn From the Crocodile How to Restore Our Hearing? (2022)
Alla publikationer
Artiklar
- The ultrastructure of a stria vascularis in the auditory organ of the cuban crocodile (Crocodylus rhombifer) (2023)
- The Acute Effects of Furosemide on Na-K-Cl Cotransporter-1, Fetuin-A and Pigment Epithelium-Derived Factor in the Guinea Pig Cochlea (2022)
- Auditory brainstem implant pitch discrimination and auditory outcome (2022)
- Unlocking the human inner ear for therapeutic intervention (2022)
- Regeneration in the Auditory Organ in Cuban and African Dwarf Crocodiles (Crocodylus rhombifer and Osteolaemus tetraspis) Can We Learn From the Crocodile How to Restore Our Hearing? (2022)
- GJB2 and GJB6 gene transcripts in the human cochlea (2022)
- Na/K-ATPase Gene Expression in the Human Cochlea (2022)
- Visualization of macrophage subsets in the development of the fetal human inner ear (2022)
- Three-Dimensional Modeling and Measurement of the Human Cochlear Hook Region (2021)
- An Approach for Individualized Cochlear Frequency Mapping Determined From 3D Synchrotron Radiation Phase-Contrast Imaging (2021)
- Aeration of the Human Prussak's Space (2021)
- Three-dimensional tonotopic mapping of the human cochlea based on synchrotron radiation phase-contrast imaging (2021)
- A Synchrotron and Micro-CT Study of the Human Endolymphatic Duct System (2021)
- Vestibular Organ and Cochlear Implantation-A Synchrotron and Micro-CT Study (2021)
- Distribution of Immune Cells Including Macrophages in the Human Cochlea (2021)
- A combined genome-wide association and molecular study of age-related hearing loss in H. sapiens (2021)
- Spike Generators and Cell Signaling in the Human Auditory Nerve (2021)
- HCN channels in the mammalian cochlea (2021)
- The proteome of the human endolymphatic sac endolymph (2021)
- Early appearance of key transcription factors influence the spatiotemporal development of the human inner ear (2020)
- Age-Dependency of Neurite Outgrowth in Postnatal Mouse Cochlear Spiral Ganglion Explants (2020)
- Characterization of the human helicotrema (2020)
- "Reversed polarization" of Na/K-ATPase — a sign of inverted transport in the human endolymphatic sac (2020)
- A Micro-CT and Synchrotron Imaging Study of the Human Endolymphatic Duct with Special Reference to Endolymph Outflow and Meniere's Disease (2020)
- Synchrotron Radiation-Based Reconstruction of the Human Spiral Ganglion (2020)
- Human cochlear microanatomy - an electron microscopy and super-resolution structured illumination study and review (2020)
- Vascular Supply of the Human Spiral Ganglion (2020)
- Cochlear implantation and residual hearing preservation long-term follow-up of the first consecutively operated patients using the round window approach in Uppsala, Sweden (2020)
- Incus Necrosis and Blood Supply (2019)
- The Human Endolymphatic Sac and Inner Ear Immunity (2019)
- Human Inner Ear Immune Activity (2019)
- Expression of Na/K-ATPase subunits in the human cochlea (2019)
- Super-resolution immunohistochemistry study on CD4 and CD8 cells and the relation to macrophages in human cochlea (2019)
- Three-dimensional imaging of the human internal acoustic canal and arachnoid cistern (2019)
- Effects of Various Trajectories on Tissue Preservation in Cochlear Implant Surgery (2019)
- Transcription and microRNA Profiling of Cultured Human Tympanic Membrane Epidermal Keratinocytes (2018)
- The secondary spiral lamina and its relevance in cochlear implant surgery (2018)
- The Human Cochlear Aqueduct and Accessory Canals (2018)
- The proteome of perilymph in patients with vestibular schwannoma (2018)
- Anatomical basis of drug delivery to the inner ear (2018)
- Expression of trans-membrane serine protease 3 (TMPRSS3) in the human organ of Corti (2018)
- Macrophages in the Human Cochlea (2018)
- Human inner ear blood supply revisited (2018)
- Special Anatomic Considerations in Otosclerosis Surgery (2018)
- Peri-operative electrically evoked auditory brainstem response assessment of facial nerve/cochlea interaction at cochlear implantation (2018)
- Three-Dimensional Analysis of the Fundus of the Human Internal Acoustic Canal (2018)
- Role of BDNF and neurotrophic receptors in human inner ear development (2017)
- Female mice lacking Pald1 exhibit endothelial cell apoptosis and emphysema (2017)
- Biofunctionalized peptide-based hydrogels provide permissive scaffolds to attract neurite outgrowth from spiral ganglion neurons (2017)
- Guided Growth of Auditory Neurons (2017)
- Molecular composition and distribution of gap junctions in the sensory epithelium of the human cochlea a super-resolution structured illumination microscopy (SR-SIM) study (2017)
- The Human "Cochlear Battery" - Claudin-11 Barrier and Ion Transport Proteins in the Lateral Wall of the Cochlea (2017)
- Re-implantation of an auditory brainstem implant (ABI) in a child (2017)
- Supernumerary human hair cells-signs of regeneration or impaired development? (2017)
- Anatomical Characteristics of Facial Nerve and Cochlea Interaction (2017)
- Effects of mechanical trauma to the human tympanic membrane (2017)
- NANOCI-Nanotechnology Based Cochlear Implant With Gapless Interface to Auditory Neurons (2017)
- Strategy towards independent electrical stimulation from cochlear implants (2016)
- The inferior cochlear vein (2016)
- The effect of pulsed electric fields on the electrotactic migration of human neural progenitor cells through the involvement of intracellular calcium signaling (2016)
- In Response to Immunohistochemical Localization of OCT2 in the Cochlea of Various Species (2016)
- Neurosensory Differentiation and Innervation Patterning in the Human Fetal Vestibular End Organs between the Gestational Weeks 8-12 (2016)
- The Human Vestibular Aqueduct (2016)
- Super-resolution structured illumination fluorescence microscopy of the lateral wall of the cochlea (2016)
- Self-Reported Benefit, Sound Perception, and Quality-of-Life in Patients with Auditory Brainstem Implants (ABIs) (2016)
- Experiences from Auditory Brainstem Implantation (ABI) in four Paediatric Patients (2016)
- Two are Better than One (2016)
- Scanning Electron Microscopic Examination of the Extracellular Matrix in the Decellularized Mouse and Human Cochlea (2016)
- Consensus statement (2016)
- Regulation of the perilymphatic-endolymphatic water shunt in the cochlea by membrane translocation of aquaporin-5 (2015)
- Hearing and Patient Satisfaction Among 19 Patients Who Received Implants Intended for Hybrid Hearing (2015)
- Carotid Artery Compression Caused by the Cochlea (2015)
- Molecular organization and fine structure of the human tectorial membrane (2015)
- Immunohistochemical localization of OCT2 in the cochlea of various species (2015)
- Macromolecular organization and fine structure of the human basilar membrane - RELEVANCE for cochlear implantation (2015)
- The Pre- and Post-Somatic Segments of the Human Type I Spiral Ganglion Neurons - Structural and Functional Considerations Related to Cochlear Implantation (2015)
- Prognostic Value of Electrically Evoked Auditory Brainstem Responses in Cochlear Implantation (2015)
- Development of the innervation of the human inner ear (2015)
- Auditory nerve preservation and regeneration in man (2015)
- On the Anatomy of the 'Hook' Region of the Human Cochlea and How It Relates to Cochlear Implantation (2014)
- Is the Human Round Window Really Round? (2014)
- Water permeability of the mammalian cochlea (2014)
- Differentiation of human neural progenitor cell-derived spiral ganglion-like neurons (2014)
- 3-D gel culture and time-lapse video microscopy of the human vestibular nerve (2014)
- Possible role of gap junction intercellular channels and connexin 43 in satellite glial cells (SGCs) for preservation of human spiral ganglion neurons (2014)
- Immunohistological analysis of neurturin and its receptors in human cochlea (2014)
- Experiences and Results from Cochlear Implantation in Patients with Long Duration of Deafness (2014)
- Auditory Brainstem Implants (ABIs) (2014)
- Round window vibroplasty in chronic ear surgery (2013)
- Non-echo planar diffusion-weighted MRI increases follow-up accuracy after one-step step canal wall-down obliteration surgery for cholesteatoma (2013)
- Surgical treatment of adult cholesteatoma (2013)
- How to predict cochlear length before cochlear implantation surgery (2013)
- Distribution of pejvakin in human spiral ganglion (2013)
- Cochlear implantation in the elderly (2013)
- Nanomedicine strategies for drug delivery to the ear (2013)
- [Assessment of Meniere's disease from a radiological aspect-saccular otoconia as a cause of Meniere's disease?] (2013)
- Water channel proteins in the inner ear and their link to hearing impairment and deafness (2012)
- Co-localisation of Kir4.1 and AQP4 in rat and human cochleae reveals a gap in water channel expression at the transduction sites of endocochlear K+ recycling routes (2012)
- Surgical treatment of paediatric cholesteatoma (2012)
- Cochlear implantation and hearing preservation (2012)
- Expression of myelin basic protein in the human auditory nerve (2012)
- Distribution of P75 neurotrophin receptor in adult human cochlea (2012)
- Human cochlea (2012)
- High frequency hearing following stapes surgery (2012)
- Assessment of Meniere's disease from a radiological aspect (2012)
- Localization of Progenitor/Stem Cells in the Human Tympanic Membrane (2011)
- Expression of TrkB and BDNF in human cochlea (2011)
- Anatomy of the human cochlea (2011)
- Auditory Brainstem Implantation in Children and Non-Neurofibromatosis Type 2 Patients (2011)
- Histology and synchrotron radiation-based microtomography of the inner ear in a molecularly confirmed case of CHARGE syndrome (2010)
- Surgical Treatment of Patients With Facial Neuromas (2010)
- Antisecretory factor-inducing therapy improves the clinical outcome in patients with Meniere's disease (2010)
- The subcellular distribution of aquaporin 5 in the cochlea reveals a water shunt at the perilymph-endolymph barrier (2010)
- Expression of peripherin in human cochlea (2010)
- Immunolocalization of prestin in human Cochlea (2010)
- Ganglion Cell and 'Dendrite' Populations in Electric Acoustic Stimulation Ears (2010)
- Studies of the human cochlea with aspects of future hearing rehabilitation (2010)
- Internalization of nanoparticles into spiral ganglion cells (2009)
- Effects of Neurotrophic Factors on Growth and Glial Cell Alignment of Cultured Adult Spiral Ganglion Cells (2009)
- Variational anatomy of the human cochlea (2009)
- Unique expression of connexins in the human cochlea (2009)
- Expression of peripherin in the pig spiral ganglion (2009)
- Hearing preservation and nanotechnology-based targted drug delivry future in cochlear implantation? (2009)
- Immunodefense of the round window (2008)
- Neural network and "Ganglion" formations in vitro (2007)
- Hjärnstamsimplantat kan återge hörsel. Behandling av dövhet vid dubbelsidiga akustikusneurinom (2007)
- Efferent neurotransmitters in the human cochlea and vestibule (2007)
- Structure and locomotion of adult in vitro regenerated spiral ganglion growth cones (2006)
- An interstitial network of podoplanin-expressing cells in the human endolymphatic duct (2006)
- Innervation of the apical turn of the human cochlea (2006)
- Perilymph/modiolar communication routes in the human cochlea (2006)
- Ultrastructure of the normal human organ of corti. new anatomical findings in surgical specimens. (2005)
- The human spiral ganglion (2005)
- High resolution scanning electron microscopy of the human organ of Corti. A study using freshly fixed surgical specimens. (2005)
- Smooth muscle in the annulus fibrosus of the tympanic membrane in bats, rodents, insectivores and humans (2005)
- Regeneration of human auditory nerve. In vitro/in video demonstration of neural progenitor cells in adult human and guinea pig spiral ganglion (2005)
- Effects of intratympanic injection of latanoprost in Meniere's disease (2005)
- [The endolymphatic sac (2004)
- Human round window membrane receptor (2004)
- Responses of the endolymphatic sac to perilymphatic injections and withdrawals (2004)
- Localization of prostanoid receptors and cyclo-oxygenase enzymes in guinea pig and human cochlea (2004)
- Network organization of interstitial connective tissue cells in the human endolymphatic duct (2003)
- Extensive network organization of cells in the connective tissue surrounding the human endolymphatic duct. Possible implications for fluid pressure control of the inner ear. (2003)
- Network organization of interstitial connective tissue cells in the human endolymphatic duct (2003)
- Synaptophysin immunohistochemistry in the human cochlea. (2003)
- Vascular occlusion in the endolymphatic sac in Ménière's disease (2002)
- In vitro growth of human endolymphatic sac cells (2001)
- High resolution deltation analysis of constitutional DNA from neurofibromatosis type 2 (NF2)patients using microarray-CGH. (2001)
- Steriocilia-like structures in the endolymphatic sac in Ménière's disease and acoustic neuroma (1998)
- Evaluation of quality of life and symptoms after translabyrinthine acoustic neuroma surgery (1997)
- Tinnitus and translabyrinthine acoustic neuroma surgery (1997)
- "Endolymphatic sacitis" in a case of active Menière's disease (1997)
- Quantitative evaluation of cochlear neurons and computer-aided three-dimensional reconstruction of spiral ganglion cells in humans with a peripheral loss of nerve fibres (1997)
- Nerve fibre interaction with large ganglion cells in the human spiral ganglion (1997)
- Cochlear changes following destruction of semicircular canal in healthy and previously toxin-exposed rats (1997)
- Neural interaction in the human spiral ganglion (1997)
- Elektrisk stimulering av hjärnstammen (1996)
- Natural killer cell response in the inner ear (1995)
Böcker
Kapitel
- Ganglion and dendritic population in EAS ears (2010)
- Pathology of the vestibular organ (2008)
- Anatomy and ultrastructure of the vestibular organ (2008)
Konferenser
