Gunnar Pejler
Professor vid Institutionen för medicinsk biokemi och mikrobiologi; Infektioner och immunitet; Gunnar Pejler
- Telefon:
- 018-471 45 71
- E-post:
- gunnar.pejler@imbim.uu.se
- Besöksadress:
- BMC
Husargatan 3
752 37 UPPSALA - Postadress:
- Box 582
751 23 UPPSALA
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Publikationer
Senaste publikationer
- A two-step activation mechanism enables mast cells to differentiate their response between extracellular and invasive enterobacterial infection (2024)
- Mast cell chymase suppresses functional parameters in primary human airway smooth muscle cells (2024)
- Tendon pain (2023)
- Nafamostat has anti-asthmatic effects associated with suppressed pro-inflammatory gene expression, eosinophil infiltration and airway hyperreactivity (2023)
- Absence of changes in the milk microbiota during Escherichia coli endotoxin induced experimental bovine mastitis (2023)
Alla publikationer
Artiklar
- A two-step activation mechanism enables mast cells to differentiate their response between extracellular and invasive enterobacterial infection (2024)
- Mast cell chymase suppresses functional parameters in primary human airway smooth muscle cells (2024)
- Tendon pain (2023)
- Nafamostat has anti-asthmatic effects associated with suppressed pro-inflammatory gene expression, eosinophil infiltration and airway hyperreactivity (2023)
- Absence of changes in the milk microbiota during Escherichia coli endotoxin induced experimental bovine mastitis (2023)
- Phenotypic Switch and Growth of Melanoma Spheroids in the Presence of Mast Cells (2023)
- Heparin and heparin proteoglycan-mimetics activate platelets via PEAR1 and PI3K beta (2023)
- Chymase Inhibition Resolves and Prevents Deep Vein Thrombosis Without Increasing Bleeding Time in the Mouse Model (2023)
- Obesity Is Associated with Distorted Proteoglycan Expression in Adipose Tissue (2023)
- Therapeutic administration of mouse mast cell protease 6 improves functional recovery after traumatic spinal cord injury in mice by promoting remyelination and reducing glial scar formation (2023)
- Monensin induces secretory granule-mediated cell death in eosinophils (2023)
- Treatment of chronic airway diseases using nutraceuticals (2022)
- Neutrophil extracellular traps promote cancer-associated inflammation and myocardial stress. (2022)
- The ingenious mast cell (2022)
- Serglycin Is Involved in Adipose Tissue Inflammation in Obesity (2022)
- Differential expression of enzymes in thymidylate biosynthesis in zebrafish at different developmental stages (2022)
- Structural and functional analysis of human thymidylate kinase isoforms (2022)
- Heavy metal tolerance of Mesorhizobium delmotii thymidylate kinase (2022)
- Mefloquine causes selective mast cell apoptosis in cutaneous mastocytosis lesions by a secretory granule-mediated pathway (2022)
- Mast cell chymase has a negative impact on human osteoblasts (2022)
- Monensin inhibits mast cell mediated airway contractions in human and guinea pig asthma models (2022)
- Quantitative In-Depth Transcriptome Analysis Implicates Peritoneal Macrophages as Important Players in the Complement and Coagulation Systems (2022)
- Mast cell tryptase potentiates neutrophil extracellular trap formation (2022)
- Tryptase reference values in a Swedish middle-aged general population and association with diabetes mellitus (2022)
- Mast cell chymase affects the functional properties of primary human airway fibroblasts (2022)
- Mast cell chymase regulates extracellular matrix remodeling-related events in primary human small airway epithelial cells (2022)
- Tryptase Regulates the Epigenetic Modification of Core Histones in Mast Cell Leukemia Cells (2021)
- Glutamate triggers the expression of functional ionotropic and metabotropic glutamate receptors in mast cells (2021)
- Platelet α-granule cargo packaging and release are affected by the luminal proteoglycan, serglycin (2021)
- Biochemical Characterizations of Human TMPK Mutations Identified in Patients with Severe Microcephaly (2021)
- Monensin induces selective mast cell apoptosis through a secretory granule-mediated pathway. (2021)
- Novel Strategies to Target Mast Cells in Disease (2021)
- Mast Cell Degranulation Increases Mouse Mast Cell Protease 4-Dependent Vasopressor Responses to Big Endothelin-1 But Not Angiotensin I (2021)
- Dynamin inhibition causes context-dependent cell death of leukemia and lymphoma cells (2021)
- Quantitative In-Depth Analysis of the Mouse Mast Cell Transcriptome Reveals Organ-Specific Mast Cell Heterogeneity (2020)
- How Relevant Are Bone Marrow-Derived Mast Cells (BMMCs) as Models for Tissue Mast Cells? (2020)
- Mast Cell β-Tryptase Is Enzymatically Stabilized by DNA (2020)
- Histone Methyltransferase Inhibition Has a Cytotoxic Impact on Transformed Mast Cells (2020)
- Do Mast Cells Have a Role in Tendon Healing and Inflammation? (2020)
- Identification of a novel thymidylate kinase activity. (2020)
- Protective role of mouse mast cell tryptase Mcpt6 in melanoma. (2020)
- Novel aspects of mast cell and basophil function (2020)
- Mast cell chymase protects against acute ischemic kidney injury by limiting neutrophil hyperactivation and recruitment (2020)
- Mouse connective tissue mast cell proteases tryptase and carboxypeptidase A3 play protective roles in itch induced by endothelin-1 (2020)
- Urticaria (2020)
- DNA demethylation regulates gene expression in IgE-activated mouse mast cells. (2020)
- Novel Insight into the in vivo Function of Mast Cell Chymase (2020)
- Experimental Autoimmune Encephalomyelitis Potentiates Mouse Mast Cell Protease 4-Dependent Pressor Responses to Centrally or Systemically Administered Big Endothelin-1 (2019)
- Local delivery of temozolomide via a biologically inert carrier (Temodex) prolongs survival in glioma patients, irrespectively of the methylation status of MGMT (2019)
- The Absence of Tryptase Mcpt6 Causes Elevated Cellular Stress in Response to Modulation of the Histone Acetylation Status in Mast Cells (2019)
- Exosome-mediated uptake of mast cell tryptase into the nucleus of melanoma cells (2019)
- Lysosomotropic challenge of mast cells causes intra-granular reactive oxygen species production (2019)
- The emerging role of mast cell proteases in asthma (2019)
- The emerging role of mast cell proteases in asthma (2019)
- Mouse Mast Cell Protease-4 Recruits Leukocytes in the Inflammatory Phase of Surgically Wounded Skin (2019)
- Mouse mast cell protease 4 suppresses scar formation after traumatic spinal cord injury (2019)
- Streptococcal sagA activates a proinflammatory response in mast cells by a sublytic mechanism (2019)
- The controversial role of mast cells in fibrosis (2018)
- Mitogen-Activated Protein Kinase Signaling Regulates Proteoglycan Composition of Mast Cell Secretory Granules (2018)
- Mast cell chymase decreases the severity of group B Streptococcus infections (2018)
- Mouse Mast Cell Protease 4 Deletion Protects Heart Function and Survival After Permanent Myocardial Infarction (2018)
- The Effect of Lipopolysaccharide-Induced Experimental Bovine Mastitis on Clinical Parameters, Inflammatory Markers, and the Metabolome (2018)
- Mouse mast cells and mast cell proteases do not play a significant role in acute tissue injury pain induced by formalin (2018)
- Mast Cell Degranulation Exacerbates Skin Rejection by Enhancing Neutrophil Recruitment (2018)
- Increased mast cell degranulation and co-localization of mast cells with the NMDA receptor-1 during healing after Achilles tendon rupture (2017)
- Inhibition of the BET family of epigenetic reader proteins (2017)
- The combined action of mast cell chymase, tryptase and carboxypeptidase A3 protects against melanoma colonization of the lung (2017)
- Siramesine causes preferential apoptosis of mast cells in skin biopsies from psoriatic lesions (2017)
- Copper Regulates Maturation and Expression of an MITF (2017)
- Excessive dietary intake of vitamin A reduces skull bone thickness in mice (2017)
- Tryptase-catalyzed core histone truncation (2017)
- Induction of Human Lung Mast Cell Apoptosis by Granule Permeabilization (2017)
- Acidic pH is essential for maintaining mast cell secretory granule homeostasis (2017)
- Mast cells and McPT4 chymase Promote renal impairment after Partial Ureteral Obstruction (2017)
- Proteome analysis of mast cell releasates reveals a role for chymase in the regulation of coagulation factor XIIIA levels via proteolytic degradation (2017)
- Equine Airway Mast Cells are Sensitive to Cell Death Induced by Lysosomotropic Agents (2017)
- Significant Contribution of Mouse Mast Cell Protease 4 in Early Phases of Experimental Autoimmune Encephalomyelitis (2016)
- Endothelin receptor antagonist macitentan or deletion of mouse mast cell protease 4 delays lesion development in atherosclerotic mice (2016)
- Mastitis Pathogens with high Virulence in a Mouse Model Produce a Distinct cytokine Profile In Vivo (2016)
- The Role of Mast Cells in Bacterial Infection (2016)
- Live Staphylococcus aureus Induces Expression and Release of Vascular Endothelial Growth Factor in Terminally Differentiated Mouse Mast Cells (2016)
- Increased Bone Mass in Female Mice Lacking Mast Cell Chymase (2016)
- Activated mast cells promote differentiation of B cells into effector cells (2016)
- Serglycin determines secretory granule repertoire and regulates natural killer cell and cytotoxic T lymphocyte cytotoxicity (2016)
- IGF-1 degradation by mouse mast cell protease 4 promotes cell death and adverse cardiac remodeling days after a myocardial infarction (2016)
- Mast cells promote scar remodeling and functional recovery after spinal cord injury via mouse mast cell protease 6 (2016)
- IL-6 and IL-17A degradation by mast cells is mediated by a serglycin (2016)
- Mast cells promote melanoma colonization of lungs (2016)
- Approaches for analyzing the roles of mast cells and their proteases in vivo (2015)
- Damnacanthal inhibits IgE receptor-mediated activation of mast cells (2015)
- Ablation of human skin mast cells in situ by lysosomotropic agents (2015)
- Serglycin protects against high fat diet-induced increase in serum LDL in mice (2015)
- Induction of mast cell apoptosis by a novel secretory granule-mediated pathway. (2015)
- MAST CELL GRANULES (2015)
- Serglycin protects against high fat diet-induced increase in plasma LDL in mice (2015)
- Chymase inhibitor-sensitive synthesis of endothelin-1 (1-31) by recombinant mouse mast cell protease 4 and human chymase (2015)
- Ctr2 Regulates Mast Cell Maturation by Affecting the Storage and Expression of Tryptase and Proteoglycans (2015)
- Nuclear Receptor 4a3 (Nr4a3) Regulates Murine Mast Cell Responses and Granule Content (2014)
- Proteolytic Histone Modification by Mast Cell Tryptase, a Serglycin Proteoglycan-dependent Secretory Granule Protease (2014)
- Mast cells are activated by Staphylococcus aureus in vitro but do not influence the outcome of intraperitoneal S. aureus infection in vivo (2014)
- Serglycin Proteoglycan Promotes Apoptotic versus Necrotic Cell Death in Mast Cells (2012)
- Altered storage of proteases in mast cells from mice lacking heparin: a possible role for heparin in carboxypeptidase A processing. (2002)
- Secretory granule proteases in rat mast cells (1997)
- Mouse mast cell tryptase and carboxypeptidase A3 play a protective role in itch induced by endothelin-1
- Compound 48/80-induced itch is attenuated by mouse mast cell tryptase and carboxypeptidase A3
