Paraskevi Heldin
Gästprofessor i bindvävsbiologi vid Institutionen för medicinsk biokemi och mikrobiologi; Cancer; Paraskevi Heldin
- Mobiltelefon:
- 070-494 59 35
- E-post:
- evi.heldin@imbim.uu.se
- Besöksadress:
- BMC
Husargatan 3
752 37 UPPSALA - Postadress:
- Box 582
751 23 UPPSALA
- Akademiska meriter:
- DMSc, docent
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Publikationer
Senaste publikationer
- Hyaluronan-Induced CD44-iASPP Interaction Affects Fibroblast Migration and Survival (2023)
- Identification of a Small Molecule Inhibitor of Hyaluronan Synthesis, DDIT, Targeting Breast Cancer Cells (2022)
- CD44 Depletion in Glioblastoma Cells Suppresses Growth and Stemness and Induces Senescence (2022)
- The natural antisense transcript HAS2-AS1 regulates breast cancer cells aggressiveness independently from hyaluronan metabolism (2022)
- Hyaluronan nanoscale clustering and Hyaluronan synthase 2 expression are linked to the invasion of child fibroblasts and infantile fibrosarcoma in vitro and in vivo (2022)
Alla publikationer
Artiklar
- Hyaluronan-Induced CD44-iASPP Interaction Affects Fibroblast Migration and Survival (2023)
- Identification of a Small Molecule Inhibitor of Hyaluronan Synthesis, DDIT, Targeting Breast Cancer Cells (2022)
- CD44 Depletion in Glioblastoma Cells Suppresses Growth and Stemness and Induces Senescence (2022)
- The natural antisense transcript HAS2-AS1 regulates breast cancer cells aggressiveness independently from hyaluronan metabolism (2022)
- Hyaluronan nanoscale clustering and Hyaluronan synthase 2 expression are linked to the invasion of child fibroblasts and infantile fibrosarcoma in vitro and in vivo (2022)
- TRAF4/6 Is Needed for CD44 Cleavage and Migration via RAC1 Activation (2021)
- Plasma hyaluronan, hyaluronidase activity and endogenous hyaluronidase inhibition in sepsis (2021)
- Plasma Hyaluronan Decreases During ICU Stay in COVID-19 Survivors but Not inNon-Survivor (2021)
- Involvement of hyaluronan and CD44 in cancer and viral infections (2020)
- Intracellular hyaluronan (2020)
- Regulation of hyaluronan biosynthesis and clinical impact of excessive hyaluronan production (2019)
- Tumor-suppressive functions of 4-MU on breast cancer cells of different ER status (2019)
- Has2 natural antisense RNA and Hmga2 promote Has2 expression during TGFβ-induced EMT in breast cancer (2019)
- Transforming growth factor β (TGFβ) induces NUAK kinase expression to fine-tune its signaling output (2019)
- High levels of serum hyaluronan is an early predictor of dengue warning signs and perturbs vascular integrity (2019)
- Effects of mutations in the post-translational modification sites on the trafficking of hyaluronan synthase 2 (HAS2) (2019)
- The role of deubiquitinating enzyme USP17, hyaluronan synthase 2, and hyaluronan in non-small-cell lung cancer oncogenic transformation (2018)
- The deubiquitinating enzymes USP4 and USP17 target hyaluronan synthase 2 and differentially affect its function (2017)
- Fluorescence Resonance Energy Transfer (FRET) and Proximity Ligation Assays Reveal Functionally Relevant Homo-and Heteromeric Complexes among Hyaluronan Synthases HAS1, HAS2, and HAS3 (2015)
- Platelet-derived Growth Factor beta-Receptor, Transforming Growth Factor beta Type I Receptor, and CD44 Protein Modulate Each Other's Signaling and Stability (2014)
- Preface (2014)
- Proteoglycans/Glycosaminoglycans (2014)
- Deregulation of hyaluronan synthesis, degradation and binding promotes breast cancer (2013)
- Efficient TGF beta-induced epithelial-mesenchymal transition depends on hyaluronan synthase HAS2 (2013)
- IQGAP1 regulates hyaluronan-mediated fibroblast motility and proliferation (2012)
- Hyaluronan accumulation in thyroid tissue (2007)
- Hyaluronan production regulation from porcine hyalocyte cell line by cytokines (2007)
- Inhibition of Platelet-derived Growth Factor-BB-induced Receptor Activation and Fibroblast Migration by Hyaluronan Activation of CD44 (2006)
- Hyaluronan and its binding proteins in the epithelium and intraluminal fluid of the bovine oviduct (2005)
- Phase I and Pharmacokinetic Evaluation of Intravenous Hyaluronic Acid in Combination with Doxorubicin or 5-Fluorouracil (2005)
- Hyaluronan fragments induce endothelial cell differentiation in a CD44- and CXCL1/GRO1-dependent manner. (2005)
- Antisense-mediated suppression of hyaluronan synthase 2 inhibits the tumorigenesis and progression of breast cancer (2005)
- Hyaluronan synthase in trabecular meshwork cells. (2003)
- Expression of hyaluronan synthase 2 or hyaluronidase 1 differentially affect the growth rate of transplantable colon carcinoma cell tumors. (2002)
- Improvement of rat liver graft function after storage in University ofWisconsin solution containing testicular hyaluronidase. (2002)
- Testicular hyaluronidase induces tubular structures of endothelial cells grown in three-dimensional collagen gel through a CD44-mediated mechanism. (2002)
- Hyaluronan production increases the malignant properties of mesotheliomacells. (2001)
- Hgf/sf induces mesothelial cell migration and proliferation by autocrineand paracrine pathways. (2001)
- Stimulatory effects of pleural fluids from mesothelioma patients on CD44 expression, hyaluronan production and cell proliferation in primary cultures of normal mesothelial and transformed cells (1996)
- Characterization of the mechanism involved in bleomycin-induced increased hyaluronan production in rat lung (1995)
Kapitel
