Wei Xia
Professor at Institutionen för materialvetenskap; Tillämpad materialvetenskap
- Telephone:
- +46 18 471 31 28
- Mobile phone:
- +46 73 789 56 86
- E-mail:
- wei.xia@angstrom.uu.se
- Visiting address:
- Ångströmlaboratoriet, Lägerhyddsvägen 1
- Postal address:
- Box 35
751 03 UPPSALA
- Academic merits:
- professor in applied materials science
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Biography
I am responsible for the research on “Biomaterials: synthesis and characterization” within the Materials in Medicine group in the Division of Applied Materials Science, Department of Materials Science and Engineering, located at the Ångström Laboratory. My research interests are mainly in biomedical materials:
- Advanced Glass Ceramics for dental applications
- Nano-structured bioactive ceramics for bone repair and regeneration
- Antipathogenic Materials
- Ceramics for DDS, e.x. Guided neuron growth, ASIT, Pain reliever, Transdermal delivery
- Additive Manufacturing in Ceramics
Publications
Selection of publications
- Size-driven phase transformation and microstructure evolution of ZrO2 nanocrystallites associated with thermal treatments (2021)
- Three-Dimensional Insights into Interfacial Segregation at the Atomic Scale in a Nanocrystalline Glass-Ceramic (2021)
- Max Phases as Nanolaminate Materials (2021)
- Ultrastrong translucent glass ceramic with nanocrystalline, biomimetic structure (2018)
- Biodegradable Si3N4 bioceramic sintered with Sr, Mg and Si for spinal fusion (2018)
- Bioceramic microneedle arrays are able to deliver OVA to dendritic cells in human skin (2018)
- Highly translucent and strong ZrO2-SiO2 nanocrystalline glass ceramic prepared by sol-gel method and spark plasma sintering with fine 3D microstructure for dental restoration (2017)
- Allergen-loaded strontium-doped hydroxyapatite spheres improve allergen-specific immunotherapy in mice (2017)
- Guided Growth of Auditory Neurons (2017)
- In-situ Synchrotron X-ray Diffraction Analysis of the Setting Process of Brushite Cement: Reaction and Crystal Growth (2017)
- Design of bioactive materials for bone repair and regeneration (2017)
- Bone forming potential of Sr doped hydroxyapatite hollow spheres in a rat vertebral bone defect model (2012)
- Mesoporous titanium dioxide coating for metallic implants (2012)
- Synthesis and release of trace elements from hollow and porous hydroxyapatite spheres (2011)
- Bone responses to ions-substituted apatite/titanium dioxide coating on titanium implants (2010)
Recent publications
- Structural Si3N4-SiO2 glass ceramics with bioactive and anti-bacterial properties (2024)
- Bulk nanobubbles as soft templates in the fabrication of inorganic core-shell particles (2023)
- Enhanced Bacteriostatic Properties of Ti Alloys by Surface Nitriding (2023)
- Liquid-phase sintering of ZrO2-based nanocrystalline glass-ceramics achieved by multielement co-doping (2023)
- Microstructure of rapidly-quenched ZrO2-SiO2 glass-ceramics fabricated by container-less aerodynamic levitation technology (2023)
All publications
Articles
- Structural Si3N4-SiO2 glass ceramics with bioactive and anti-bacterial properties (2024)
- Bulk nanobubbles as soft templates in the fabrication of inorganic core-shell particles (2023)
- Enhanced Bacteriostatic Properties of Ti Alloys by Surface Nitriding (2023)
- Liquid-phase sintering of ZrO2-based nanocrystalline glass-ceramics achieved by multielement co-doping (2023)
- Microstructure of rapidly-quenched ZrO2-SiO2 glass-ceramics fabricated by container-less aerodynamic levitation technology (2023)
- Structural integrity and damage of glass-ceramics after He ion irradiation (2023)
- Far from equilibrium ultrafast high-temperature sintering of ZrO2-SiO2 nanocrystalline glass-ceramics (2023)
- Microsupercapacitors Working at 250 °C (2023)
- Amorphous Calcium Magnesium Fluoride Phosphate — Novel Material for Mineralization in Preventive Dentistry (2023)
- Low-temperature and flexible strategy to in-situ fabricate ZrSiO4-based ceramic composites via doping and tuning solid-state reaction (2023)
- Iontophoresis-Driven Microneedle Arrays Delivering Transgenic Outer Membrane Vesicles in Program that Stimulates Transcutaneous Vaccination for Cancer Immunotherapy (2023)
- Effects of N/Si ratio on mechanical properties of amorphous silicon nitride coating (2023)
- Magnetic metal-organic frameworks for efficient removal of cadmium(II), and lead(II) from aqueous solution (2022)
- Doping of tantalum, niobium, and hafnium in a translucent ZrO2-SiO2 nanocrystalline glass-ceramic (2022)
- Understanding microstructure-mechanical properties relationship in ZrO2-SiO2 nanocrystalline glass-ceramics (2022)
- New insights into the formation mechanism of zircon in a ZrO2-SiO2 nanocrystalline glass-ceramic (2022)
- The Influence of Residuals Combining Temperature and Reaction Time on Calcium Phosphate Transformation in a Precipitation Process (2022)
- Bioactive Silicon Nitride Implant Surfaces with Maintained Antibacterial Properties (2022)
- Effects of surface treatment and shade on the color, translucency, and surface roughness of high-translucency self-glazed zirconia materials (2022)
- Combining good mechanical properties and high translucency in yttrium-doped ZrO2-SiO2 nanocrystalline glass-ceramics (2022)
- Effects of dopants with various valences on densification behavior and phase composition of a ZrO2-SiO2 nanocrystalline glass-ceramic (2022)
- Sequential macrophage transition facilitates endogenous bone regeneration induced by Zn-doped porous microcrystalline bioactive glass (2021)
- Comparative study of technologies for tubule occlusion and treatment of dentin hypersensitivity (2021)
- Injectable tricalcium phosphate/calcium sulfate granule enhances bone repair by reversible setting reaction (2021)
- Size-driven phase transformation and microstructure evolution of ZrO2 nanocrystallites associated with thermal treatments (2021)
- Three-Dimensional Insights into Interfacial Segregation at the Atomic Scale in a Nanocrystalline Glass-Ceramic (2021)
- Max Phases as Nanolaminate Materials (2021)
- Fabrication and characterization of bioactive zirconia-based nanocrystalline glass-ceramics for dental abutment (2021)
- Entrapment of a Cytotoxic Drug into the Crystal Structure of Calcite for Targeted Drug Delivery (2021)
- The use of heat to deliver fentanyl via pulmonary drug delivery (2021)
- Oral administration of zolpidem tartrate in an abuse-deterrent formulation versus an immediate release formulation in beagle dogs (2021)
- Synthesis and assessment of metallic ion migration through a novel calcium carbonate coating for biomedical implants (2020)
- Amorphous Calcium Magnesium Phosphate Particles for Treatment of Dentin Hypersensitivity (2020)
- Electron microscopy evaluation of mineralization on peritubular dentin with amorphous calcium magnesium phosphate microspheres (2020)
- Glass-Ceramics in Dentistry (2020)
- Observation of yttrium oxide segregation in a ZrO2-SiO2 glass-ceramic at nanometer dimensions (2020)
- Injectable and assembled 3D solid structure for free-to-fixed shape in bone reconstruction (2020)
- Enhancement of osteoblast cells osteogenic differentiation and bone regeneration by hydroxyapatite/phosphoester modified poly(amino acid) (2020)
- Microstructures and mechanical properties of Al2O3/YAG:Ce3+ eutectics with different Ce3+ concentrations grown by HDS method (2020)
- Synthesis and assessment of metallic ion migration through a novel calcium carbonate coating for biomedical implants (2019)
- Ion substitution induced formation of spherical ceramic particles (2019)
- Nano-Structure Designing Promotion Osseointegration of Hydroxyapatite Coated Ti-6Al-4V Alloy Implants in Diabetic Model (2019)
- Functionalization and patterning of nanocellulose films by surface-bound nanoparticles of hydrolyzable tannins and multivalent metal ions (2019)
- Strontium-Substituted Dicalcium Silicate Bone Cements with Enhanced Osteogenesis Potential for Orthopaedic Applications (2019)
- Microstructures and mechanical properties of Al2O3/YAG:Ce3+ eutectics with different Ce3+concentrations grown by HDS method (2019)
- Comparison of Decellularized Cow and Human Bone for Engineering Bone Grafts with Human Induced Pluripotent Stem Cells (2019)
- Enhanced luminous efficacy of transparent Ce3+ (2019)
- An injectable continuous stratified structurally and functionally biomimetic construct for enhancing osteochondral regeneration (2019)
- Cemented injectable multi-phased porous bone grafts for the treatment of femoral head necrosis (2019)
- Preparation of magnetic MnFe2O4-Cellulose aerogel composite and its kinetics and thermodynamics of Cu(II) adsorption (2018)
- Spark plasma sintering of biodegradable Si3N4 bioceramic with Sr, Mg and Si as sintering additives for spinal fusion (2018)
- Ultrastrong translucent glass ceramic with nanocrystalline, biomimetic structure (2018)
- Biodegradable Si3N4 bioceramic sintered with Sr, Mg and Si for spinal fusion (2018)
- Calcium Phosphate Microspheres as a Delivery Vehicle for Tooth-Bleaching Agents (2018)
- Conjugation of cyclodextrin to magnetic Fe3O4 nanoparticles via polydopamine coating for drug delivery (2018)
- Injectable nano-structured silicon-containing hydroxyapatite microspheres with enhanced osteogenic differentiation and angiogenic factor expression (2018)
- Near-infrared light-activated red-emitting upconverting nanoplatform for T-1-weighted magnetic resonance imaging and photodynamic therapy (2018)
- Bioceramic microneedle arrays are able to deliver OVA to dendritic cells in human skin (2018)
- Highly translucent and strong ZrO2-SiO2 nanocrystalline glass ceramic prepared by sol-gel method and spark plasma sintering with fine 3D microstructure for dental restoration (2017)
- Preparation of High Percentage α-Calcium SulfateHemihydrate via a Hydrothermal Method (2017)
- Allergen-loaded strontium-doped hydroxyapatite spheres improve allergen-specific immunotherapy in mice (2017)
- Stem cell-mediated functionalization of titanium implants (2017)
- Guided Growth of Auditory Neurons (2017)
- In-situ Synchrotron X-ray Diffraction Analysis of the Setting Process of Brushite Cement: Reaction and Crystal Growth (2017)
- Classification and Effects of Implant Surface Modification on the Bone (2017)
- Critical cracking thickness of calcium phosphates biomimetic coating (2017)
- Intra-bone marrow injection of trace elements co-doped calcium phosphate microparticles for the treatment of osteoporotic rat (2017)
- Biomineralization on Single Crystalline Rutile (2016)
- Utilization of Translucent Hydroxyapatite Nano-Ceramics as a Bio-Window Material (2016)
- Enhanced bioactivity of glass ionomer cement by incorporating calcium silicates (2016)
- Enhanced bioactivity of glass ionomer cement by incorporating calcium silicates (2016)
- Synthesis of calcium phosphate crystals with thin nacreous structure (2016)
- Synthesis of Ag doped calcium phosphate particles and their antibacterial effect as additives in dental glass ionomer cements (2016)
- Cytotoxicity of modified glass ionomer cement on odontoblast cells (2016)
- Compressive fatigue limit of four types of dental restorative materials (2016)
- Guided bone regeneration using resorbable membrane and different bone substitutes (2016)
- Transparent single crystalline ZrO2-SiO2 glass nanoceramic sintered by SPS (2016)
- Allergen-loaded strontium-doped hydroxyapatite spheres improve allergen-specific immunotherapy in mice (2016)
- Novel microparticles create a slow releasing depot for long-term immunostimulation in allergen-specific immunotherapy (2016)
- Evaluation of Biocompatibility and Release of Reactive Oxygen Species of Aluminum Oxide-Coated Materials (2016)
- In vivo and in vitro evaluation of hydroxyapatite nanoparticle morphology on the acute inflammatory response (2016)
- Bioactive spheres (2016)
- Bioceramic microneedles with flexible and self-swelling substrate (2015)
- Fabrication of translucent nanoceramics via a simple filtration method (2015)
- Highly repeatable synthesis of nHA with high aspect ratio (2015)
- Influence of alkali metal additives on phase transition of translucent ZrO2/SiO2 glass ceramics prepared by a sol-gel method (2015)
- Influence of alkali metal additives on phase transition of translucent ZrO2/SiO2 glass ceramics prepared by a sol-gel method (2015)
- The influence of Sr content in calcium phosphate coatings (2015)
- Biomimetic calcium phosphate coating of additively manufactured porous CoCr implants (2015)
- Inflammatory response to nano- and microstructured hydroxyapatite (2015)
- Influence of hydroxyapatite nanoparticle morphology on inflammatory response (2015)
- Influence of hydroxyapatite nanoparticle morphology on inflammatory response (2015)
- Enhanced drug delivery of antibiotic-loaded acrylic bone cements using calcium phosphate spheres (2015)
- Self-setting bioceramic microscopic protrusions for transdermal drug delivery (2014)
- Molecular and structural patterns of bone regeneration in surgically created defects containing bone substitutes (2014)
- Controlling Osteogenic Differentiation through Nanoporous Alumina (2014)
- Hydroxyapatite coating affects the Wnt signaling pathway during peri-implant healing in vivo (2014)
- Preparation and in vitro evaluation of strontium-doped calcium silicate/gypsum bioactive bone cement (2014)
- Strontium-Doped Calcium Phosphate and Hydroxyapatite Granules Promote Different Inflammatory and Bone Remodelling Responses in Normal and Ovariectomised Rats (2013)
- Effect of Calcium and Strontium on Mesoporous Titania Coatings for Implant Applications (2013)
- Osteogenic potential of Sr-doped calcium phosphate hollow spheres in vitro and in vivo (2013)
- The effect of Si-doping on the release of antibiotic from hydroxyapatite coatings (2013)
- Influence of surface treatments on the bioactivity of Ti (2013)
- Effect of strontium ions on the early formation of biomimetic apatite on single crystalline rutile (2013)
- Ion Substitution of Bioceramics: The Role of Ions (2013)
- Apatite Coatings: Ion Substitution and Biological Properties (2013)
- Bone tissue reactions to biomimetic ion-substituted apatite surfaces on titanium implants (2012)
- Bone forming potential of Sr doped hydroxyapatite hollow spheres in a rat vertebral bone defect model (2012)
- Strontium and silicon co-doped apatite coating: (2012)
- Incorporation of active ions into calcium phosphate coatings, their release behavior and mechanism (2012)
- Nano grain sized zirconia–silica glass ceramics for dental applications (2012)
- Mesoporous titanium dioxide coating for metallic implants (2012)
- Highly packed and aligned fluoride substituted hydroxyapatite via a surfactant-free process (2012)
- Understanding the influence of alendronate on the morphology and phase transformation of apatitic precursor nanocrystals (2012)
- Titanium carbide derived nanoporous carbon for supercapacitor applications (2012)
- Synthesis and release of trace elements from hollow and porous hydroxyapatite spheres (2011)
- Preparation and characterization of ion doped calcium phosphate spheres (2011)
- Studies of early growth mechanisms of hydroxyapatite on single crystalline rutile (2010)
- Bioactive glass scaffold with similar structure and mechanical properties of cancellous bone (2010)
- Biomineralized strontium-substituted apatite/titanium dioxide coating on titanium surfaces (2010)
- Changes of Surface Composition and Morphology after Incorporation of Ions into Biomimetic Apatite Coating (2010)
- Bubble-assisted fabrication of calcium phosphate core–shell particles
- Bioceramic microneedles with flexible and self-swelling substrate
- Controlling bioactivity of glass ionomer cement by incorporating calcium silicates
- Wear performance of a new biocompatible silicon nitride for biomedical applications
- The influence of residual ions on calcium phosphate transformation in a solution-based process: a TEM analysis
- Contact inactivation of human adenovirus type 5 by silicon nitride ceramics
- The addition of silicon nitride to PMMA bone cements reduces bacterial attachment while supporting pre-osteoblast viability
- Antiviral Properties of Oxidized Silicon Nitride Against SARS-CoV-2
- A study for tooth bleaching via carbamide peroxide loaded hollow calcium phosphate spheres
- Entrapment of Glycine Into the Crystal Structure of Nanocrystalline Hydroxyapatite by a Controlled Precipitation Method
Books
- Design of bioactive materials for bone repair and regeneration (2017)
- Design of Bioactive Materials for Bone Repair and Regeneration (2016)
Chapters
- Biological effect of ions in calcium phosphates on bone regeneration (2017)
- Biological Effect of Ions in CalciumPhosphates on Bone Regeneration (2016)
- Biomimetic preparation and biomineralization of bioceramics (2012)
- Morphology control of hydroxyapatite crystal and its aggregates (2012)
- Dental Implant Surfaces Implant Dentistry - A Rapidly Evolving Practic (2011)
- Biomimetic Hydroxyapatite Deposition on Titanium Oxide Surfaces for Biomedical Application (2011)
Conferences
- Evaporation of fentanyl from ceramics for pulmonary drug delivery (2021)
- Ceramic dental implant with enhanced bioactivity and antibacterial property (2020)
- ACP-Mg particles for treatment of dental hypersensitivity (2019)
- Synthesis of Ion Substituted Ceramic Core-Shell Particles for Dental Applications (2018)
- In-situ analysis of the fast setting reaction of brushite cement (2017)
- Synthesis and characterization of monetite with thin nacre-like structure (2016)
- In vitro cytotoxicity of dental cements on odontoblast cells (2016)
- Synthesis and characterization of monetite with thin nacreous structure (2016)
- Quasi-static compressive strength and compressive fatigue limit of dental cements (2016)
- Spark plasma sintering consolidated transparent ZrO2- SiO2 glass ceramic containing nano-sized ZrO2 spheres (2016)
- The effect of concentration of HA nanoparticles on occlusion of dental tubules for treating dentinal sensitivity (2016)
- Bioceramic microneedles in allergen-specific immunotherapy (2016)
- Calcium phosphate hollow spheres: carriers and repair (2016)
- Handling and setting properties of a bioactive glass ionomer cement (2015)
- Influences of alkali metals additives on phase transition of translucent ZrO2/SiO2 glass ceramic prepared by sol-gel method (2015)
- Influence of hydroxyapatite nanoparticle morphology on inflammatory response (2015)
- The effect of concentration of HA nanoparticles on occlusion of dental tubules for treating dentinal sensitivity (2015)
- Development and evaluation of self-setting bioceramic microneedles (2014)
- Development and evaluations of self-setting bioceramics microneedles (2014)
- Two Paste-type Glass Ionomer Cement (2014)
- Glass Ionomer Cement Modified by White Portland Cement (2014)
- The influence of heat treatment on the phase development of titania and its ability to nucleate apatite (2014)
- Hexagonal ion doped Calcium phosphates (2014)
- Enhanced bleaching effect by combining hollow calcium phosphate spheres (2014)
- Calcium phosphate spheres incorporated into PMMA cement for enhanced antibacterial properties (2014)
- Biological Effects of Strontium-Doped Calcium Phosphate and Hydroxyapatite Granules during Bone Healing in Normal and Ovariectomised Rats (2013)
- Hydroxyapatite Coating with Li+ Affects the Wnt Signaling Pathway in vivo (2013)
- Bioceramic in Dentistry and Orthopedics: ”OLD”/”NEW” (2013)
- Biological properties of ion substituted apatite coatings (2013)
- Mesoporous titania implant coatings with and without calcium and strontium ion incorporation (2012)
- In vivo and in vitro performance of Sr-doped hydroxyapatite composite in the form of hollow nano-spheres (2012)
- Apatite coating co-doped with strontium and fluoride using a biomineralization method (2012)
- Structural characterization of mesoporous titania containing silver nanoparticle inclusions for antibacterial implant applications (2012)
- Structural characterization of mesoporous titania containing silver nanparticle inclusions for antibacterial implant applications (2012)
- Evaluation of CaP spherical particles on rat osteoblasts (2012)
- Strontium doped calcium phosphate spheres: dentinal tubules filler and tooth remineralization (2012)
- Calcium phosphate sphere/PMMA composite: preparation, ion and drug release (2012)
- Translucent zirconia-silica glass ceramics for dental crowns (2012)
- Nano grain sized silica-zirconia glass ceramics for dental applications (2012)
- Self-assembled hollow hydroxyapatite spheres for ion and drug delivery (2011)
- Well-ordered mesoporous titanium dioxide coating for metallic implants (2011)
- Preparation and characterization of ion doped calcium phosphate spheres (2011)
- Early bone tissue responses to a slicon-substituted apatite/titanium dioxide coating on titanium implant (2010)
- Bone responses to ions-substituted apatite/titanium dioxide coating on titanium implants (2010)
- Co-substituted strontium and silicon apatite coatings for metallic implants (2010)
- Biomimetic ion substituted hydroxyapatite coatings on titanium for orthopedic implants (2010)
- Biomimetic hydroxyapatite growth on titanium oxide surfaces (2010)
- Biomimetic fluoride hydroxyapatite coating on dental implants (2010)
- Co-mineralization of fluoride substitued hydroxyapatite/TiO2 coating on Ti implants through a biomineralization process (2009)
- Co-mineralization of strontium substituted hydroxyapatite on polycrystalline rutile surface through a biomineralization process (2009)
- Biomimetic ion substituted apatite coating on titanium implants (2009)
Patents
- Injectable bone graft (2018)
- A transdermal drug administration device (2018)
- A transdermal drug administration device (2018)
- Hollow calcium phosphate particles (2018)
- Hollow calcium phosphate particles (2018)
- Hollow calcium phosphate particles (2018)
- Translucent nanocrystalline glass ceramic (2018)
- Si3N4 ceramic for orthopedic applications (2017)
- Method for manufacturing of spherical calcium phosphate particles (2016)
- A transdermal drug administration device (2016)
- A transdermal drug administration device (2016)
- Ion substituted calcium phosphate particles (2016)
- Ultra high strength and translucent naocrystalline glass ceramic (2016)
- A transdermal drug administration device (2015)
- Ion substituted calcium phosphate particles (2015)
- Glass ceramic material and method (2014)
- Glass ceramic material and method (2014)
- Hollow calcium phosphate particles (2014)
- Hollow calcium phosphate particles (2013)
- Ion substituted calcium phosphate particles (2011)
- Ion substituted calcium phosphate particles (2010)
- Ion substituted calcium phosphate particles (2010)
- Ion substituted hydroxyapatite coatings (2009)
- Surface coating for biomedical application (2009)