Per Larsson
Senior Lecturer/Associate Professor at Department of Pharmacy; Molecular Pharmaceutics
- Telephone:
- +46 18 471 53 96
- E-mail:
- per.r.larsson@uu.se
- Visiting address:
- Biomedicinskt Centrum BMC, Husargatan 3
752 37 Uppsala - Postal address:
- Box 580
751 23 UPPSALA
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Publications
Selection of publications
- Molecular Dynamics Simulations as a Tool to Understand Drug Solubilization in Pharmaceutical Systems (2023)
- Molecular Dynamics Simulations of Self-Assembling Colloids in Fed-State Human Intestinal Fluids and Their Solubilization of Lipophilic Drugs (2023)
- Aggregation Behavior of Structurally Similar Therapeutic Peptides Investigated by H-1 NMR and All-Atom Molecular Dynamics Simulations (2022)
- Explicit-pH Coarse-Grained Molecular Dynamics Simulations Enable Insights into Restructuring of Intestinal Colloidal Aggregates with Permeation Enhancers (2022)
- Stabilizing Mechanisms of β-Lactoglobulin in Amorphous Solid Dispersions of Indomethacin (2022)
- In Silico-Based Experiments on Mechanistic Interactions between Several Intestinal Permeation Enhancers with a Lipid Bilayer Model (2022)
- Influence of Bile Composition on Membrane Incorporation of Transient Permeability Enhancers (2020)
- MkVsites (2020)
- Aggregation Behavior of Medium Chain Fatty Acids Studied by Coarse-Grained Molecular Dynamics Simulation (2019)
- Molecular simulation as a computational pharmaceutics tool to predict drug solubility, solubilization processes and partitioning (2019)
- Computational prediction of drug solubility in water-based systems (2018)
Recent publications
- Molecular dynamics study on micelle-small molecule interactions (2024)
- Analysis of stabilization mechanisms in β-lactoglobulin-based amorphous solid dispersions by experimental and computational approaches (2024)
- Revealing the interaction between peptide drugs and permeation enhancers in the presence of intestinal bile salts (2023)
- Molecular Dynamics Simulations as a Tool to Understand Drug Solubilization in Pharmaceutical Systems (2023)
- Numerical simulation of peristalsis to study co-localization and intestinal distribution of a macromolecular drug and permeation enhancer (2023)
All publications
Articles
- Molecular dynamics study on micelle-small molecule interactions (2024)
- Analysis of stabilization mechanisms in β-lactoglobulin-based amorphous solid dispersions by experimental and computational approaches (2024)
- Revealing the interaction between peptide drugs and permeation enhancers in the presence of intestinal bile salts (2023)
- Numerical simulation of peristalsis to study co-localization and intestinal distribution of a macromolecular drug and permeation enhancer (2023)
- Molecular Dynamics Simulations of Self-Assembling Colloids in Fed-State Human Intestinal Fluids and Their Solubilization of Lipophilic Drugs (2023)
- Aggregation Behavior of Structurally Similar Therapeutic Peptides Investigated by H-1 NMR and All-Atom Molecular Dynamics Simulations (2022)
- Explicit-pH Coarse-Grained Molecular Dynamics Simulations Enable Insights into Restructuring of Intestinal Colloidal Aggregates with Permeation Enhancers (2022)
- Stabilizing Mechanisms of β-Lactoglobulin in Amorphous Solid Dispersions of Indomethacin (2022)
- In Silico-Based Experiments on Mechanistic Interactions between Several Intestinal Permeation Enhancers with a Lipid Bilayer Model (2022)
- TIRF Microscopy‐Based Monitoring of Drug Permeation Across a Lipid Membrane Supported on Mesoporous Silica (2021)
- Molecular dynamics simulations reveal membrane interactions for poorly water-soluble drugs (2021)
- Sustainability in drug discovery (2021)
- Influence of Bile Composition on Membrane Incorporation of Transient Permeability Enhancers (2020)
- MkVsites (2020)
- Molecular Dynamics Simulations on Interindividual Variability of Intestinal Fluids (2020)
- Aggregation Behavior of Medium Chain Fatty Acids Studied by Coarse-Grained Molecular Dynamics Simulation (2019)
- Molecular simulation as a computational pharmaceutics tool to predict drug solubility, solubilization processes and partitioning (2019)
- Computational prediction of drug solubility in water-based systems (2018)
- Characterization of Solubilizing Nanoaggregates Present in Different Versions of Simulated Intestinal Fluid (2017)
- Mechanism-based selection of stabilization strategy for amorphous formulations (2017)
- Molecular Structuring and Phase Transition of Lipid-Based Formulations upon Water Dispersion (2017)
- Partitioning into Colloidal Structures of Fasted State Intestinal Fluid Studied by Molecular Dynamics Simulations (2016)
- Drug solubilization in dog intestinal fluids with and without administration of lipid-rich formulations
Chapters
