Cesar Augusto Fortes Lima

Cesar Fortes-Lima (cesar.fortes-lima@ebc.uu.se) is specialized in Human Population Genetics and currently works at the sub-Department of Human Evolution at Uppsala University (Sweden) as a Researcher. He has a Doctorate in Biological Anthropology. His main research areas include African genetic diversity, African Diaspora, transatlantic slave trade, demographic inference, admixture dynamics, mass migrations. His research is mostly conducted in Africa and Latin America.

2021 – 2023 : Researcher in Population Genomics of African populations, Schlebusch Lab, Human Evolution, Evolutionary Biology Centre, Uppsala University, Uppsala, Sweden.

2018 – 2020 : Postdoc in Population Genomics of African populations, Human Evolution, Evolutionary Biology Centre, Uppsala University, Uppsala, Sweden. Adviser: Carina M. Schlebusch.

2016 – 2018 : Postdoc in Population Genetics and Bioinformatics, Mankind museum, CNRS-MNHN-University Paris Diderot, Paris, France. Adviser: Paul Verdu.

2012 – 2015 : PhD in Biological Anthropology, Faculty of Medicine, University Paul Sabatier (UPS), Toulouse, France. Adviser: Jean-Michel Dugoujon. Thesis Defense date: 17th December 2015. PhD thesis dissertation: http://thesesups.ups-tlse.fr/2957/.

2011 – 2012 : MSc in Tropical Parasitic Diseases, Faculty of Pharmacy, University of Valencia (UV), Valencia, Spain. Adviser: Santiago Mas-Coma.

2009 – 2011 : MSc in Physical Anthropology (“Evolution and Human Biodiversity”), Autonomy University of Madrid (UAM), Madrid, Spain. Adviser: Rosario Calderon.

2003 – 2009 : BSc in Biology, Complutense University of Madrid (UCM), Madrid, Spain.

Fortes-Lima CA, Burgarella C, Hammarén R, Eriksson A, Vicente M, Jolly C, Semo A, Gunnink H, Pacchiarotti S, Mundeke L, Matonda I, Muluwa J, Coutros P, Nyambe T, Cikomola C, Coetzee V, de Castro M, Ebbesen P, Delanghe J, Stoneking M, Barham L, Lombard M, Meyer A, Steyn M, Malmström H, Rocha J, Soodyall H, Pakendorf B, Bostoen K, and Schlebusch CM. (2024) The genetic legacy of the expansion of Bantu-speaking peoples in Africa. Nature 625(7995):540-547. PMID: 38030719. doi: 10.1038/s41586-023-06770-6

Sandoval-Velasco M, Jagadeesan A, Ramos-Madrigal J, Ávila-Arcos MC, Fortes-Lima CA, Watson J, Johannesdóttir E, Cruz-Dávalos DI, Gopalakrishnan S, Moreno-Mayar JV, Niemann J, Renaud G, Robson-Brown K, Bennett H, Pearson A, Helgason A, Gilbert MTP, and Schroeder H. (2023) The ancestry and geographical origins of St Helena’s Liberated Africans. American Journal of Human Genetics (AJHG) 110(9):1590-1599. PMID: 37683613. doi: 10.1016/j.ajhg.2023.08.001

Laurent R, Szpiech ZA, da Costa SS, Thouzeau V, Fortes-Lima CA, Dessarps-Freichey F, Lémée L, Utgé J, Rosenberg NA, Baptista M, and Verdu P. (2023) A genetic and linguistic analysis of the admixture histories of the islands of Cabo Verde. eLife 12:e79827. PMID: 37096877. doi: 10.7554/eLife.79827

Černý V, Priehodová E, Fortes-Lima C. (2023) A population genetic perspective on subsistence systems in the Sahel/Savannah belt of Africa and the historical role of pastoralism. Genes 14(3): 758. Note: This article belongs to the Section “Population and Evolutionary Genetics and Genomics”. PMID: 36981029. doi: 10.3390/genes14030758

Alva O, Anaïs L, Margit H, Pereda-Loth V, Tisseyre L, Boland A, Deleuze JF, Rocha J, Schlebusch C, Fortes-Lima C, Stoneking M, Radimilahy C, Rakotoarisoa JA, Letellier T, and Denis P. (2022) Extensive changes in Madagascar biodiversity and landscape are contemporaneous with major events in the history of the Malagasy human population. Current Biology 32(23):4997-5007.e5. PMID: 36334586. doi: 10.1016/j.cub.2022.09.060

Fortes-Lima CA, Tříska P, Čížková M, Podgorná E, Diallo MY, Schlebusch CM, and Černý V. (2022) Demographic and selection histories of populations across the Sahel/Savannah belt. Molecular Biology and Evolution (MBE) 39(10):msac209. Open Access. PMID: 36173804. doi: 10.1093/molbev/msac209

Breton G, Fortes-Lima C, and Schlebusch C. (2021) Revisiting the demographic history of Central African populations from a genetic perspective. Human Population Genetics and Genomics (HPGG) 1(1):0004. Note: Invited review for Special Issue on “Luca Cavalli-Sforza’s legacy, 99 years after his birth”. Open Access. doi: 10.47248/hpgg2101010004

Sengupta D, Choudhury A, Fortes-Lima C, Aron S, Whitelaw G, Bostoen K, Gunnink H, Chousou-Polydouri N, Delius P, Tollman S, Gomez-Olive Casas F, Norris S, Mashinya F, Alberts M, Hazelhurst S, Schlebusch CM, and Ramsay M. (2021) Genetic-substructure and complex demographic history of South-African Bantu-speakers. Nature Communications (Nature Comm) 12(1):2080. Open Access. PMID: 33828095. doi: 10.1038/s41467-021-22207-y

Fortes-Lima C, Laurent R, Thouzeau V, Toupance B, and Verdu P. (2021) Complex genetic admixture histories reconstructed with Approximate Bayesian Computation. Molecular Ecology Resources (Mol Ecol Resour) 21(4):1098–1117. PMID: 33452723. doi: 10.1111/1755-0998.13325

Fortes-Lima C and Verdu P. (2021) Anthropological Genetics Perspectives on the Transatlantic Slave Trade. Human Molecular Genetics (HMG). 30(R1):R79–R87. Note: Invited review for the HMG Specialist Review Issue entitled “Evolutionary Genomics in Africa”. PMID: 33331897. doi: 10.1093/hmg/ddaa271

Černý V, Fortes-Lima C and Tříska P. (2021) Demographic history and admixture dynamics in African Sahelian populations. Human Molecular Genetics (HMG). 30(R1):R29–R36. Note: Invited review for the HMG Specialist Review Issue entitled “Evolutionary Genomics in Africa”. PMID: 33105478. doi: 10.1093/hmg/ddaa239

Fortes-Lima C and Schlebusch C. (2021) Closing the gaps in genomic research. Spotlight article. Trends in Genetics. 37(2):104-106. PMID: 33246657. doi: 10.1016/j.tig.2020.11.005

Debortoli G., Santana de Araujo G., Fortes-Lima C., Parra E.J., and Suarez-Kurtz G. (2021) Identification of ancestry proportions in admixed groups across the Americas using three clinical pharmacogenomic SNP panels. Scientific Reports 11(1):1007. PMID: 33441860. doi: 10.1038/s41598-020-80389-9

Bouakaze C., Delehelle F., Saenz-Oyhéréguy N., Schiavinato S., Moreira A., Croze M., Delon S., Fortes-Lima C., Gibert M., Bujan L., Huyghe E., Bellis G., Calderon R., Hernández C.L., Avendaño-Tamayo E., Bedoya G., Salas A., Mazières S., Chiaroni J., Migot-Nabias F., Ruiz-Linares A., Dugoujon J.-M., Thèves C., Mollereau-Manauté C., Poulet N., King T., D'Amato M.E., Balaresque P. (2020) Predicting haplogroups using a versatile machine learning program (PredYMaLe) on a new mutationally balanced 32 Y-STR multiplex (CombYplex): unlocking the full potential of the human STR mutation rate spectrum to estimate forensic parameters. Forensic Sciences International-Genetics (FSIG) 48:102342. PMID: 32818722. doi: 10.1016/j.fsigen.2020.102342

Debortoli G., Abbatangelo C., Ceballos F., Fortes-Lima C., Norton H.L., Ozarkar S., Parra E.J., Jonnalagadda M. (2020) Novel insights on demographic history of tribal and caste groups from West Maharashtra (India) using genome-wide data. Scientific Reports 2020. 10(1):10075. Open Access. PMID: 32572090. doi: 10.1038/s41598-020-66953-3

Semo A., Gayà-Vidal M., Fortes-Lima C., Alard B., Oliveira S., Almeida J., Prista A., Damasceno A., Fehn A.M., Schlebusch C., Rocha J. (2020). Along the Indian Ocean coast: genomic variation in Mozambique provides new insights into the Bantu expansion. Molecular Biology and Evolution. doi: 10.1093/molbev/msz224.

Fortes-Lima C., Laurent R., Thouzeau V., Toupance B., Verdu P. (2019). Complex genetic admixture histories reconstructed with Approximate Bayesian Computations. bioRxiv 761452.

Fortes-Lima C., Mtetwa E., Schlebusch C. (2019). Unraveling African diversity from a cross‐disciplinary perspective. Evolutionary Anthropology. doi: 10.1002/evan.21801.

Lona-Durazo F., Hernandez-Pacheco N., Fan S., Zhang T., Choi J., Kovacs M.A., Loftus S.K., Le P., Edwards M., Fortes-Lima C.A., Eng C., Huntsman S., Hu D., Gómez-Cabezas E.J., Marín-Padrón L.C., Grauholm J., Mors O, Burchard E.G., Norton H.L., Pavan W.J., Brown K.M., Tishkoff S., Pino-Yanes M., Beleza S., Marcheco-Teruel B., Parra E.J. (2019). Meta-analysis of GWA studies provides new insights on the genetic architecture of skin pigmentation in recently admixed populations. BMC Genetics 20(1):59. doi: 10.1186/s12863-019-0765-5. PMID: 31315583.

Fortes-Lima C., Bybjerg-Grauholm J., Marin-Padrón L.C., Gomez-Cabezas E.J., Bækvad-Hansen M., Hansen C.S., Le P., Hougaard D.M., Verdu P., Mors O., Parra E.J., Marcheco-Teruel B. (2018). Exploring Cuba's population structure and demographic history using genome-wide data. Scientific Reports 8(1):11422. doi: 10.1038/s41598-018-29851-3. PMID: 30061702.

Fortes-Lima C. and Dugoujon J.M. (2018). Revisiting genetic ancestry in African Diaspora communities from Atlantic South America. Scientific Chapter Book. Book: Trends in Biological Anthropology, Volume: 2. Editors: Jakob B. and Holst M. Publisher: Oxbow Books, United Kingdom. ISBN-13: 9781785706202. doi: https://www.jstor.org/stable/j.ctvh1dmwc.6

Jagadeesan A., Gunnarsdóttir E.D., Ebenesersdóttir S.S., Guðmundsdóttir V.B., Thordardottir E.L., Einarsdóttir M.S., Jónsson H., Dugoujon J.M., Fortes-Lima C., Migot-Nabias F., Massougbodji A., Bellis G., Pereira L., Másson G., Kong A, Stefánsson K., Helgason A. (2018). Reconstructing an African haploid genome from the 18th century. Nature Genetics 50(2):199-205. doi: 10.1038/s41588-017-0031-6. PMID: 29335549.

Fortes-Lima C., Gessain A., Ruiz-Linares A., Bortolini M.C., Migot-Nabias F., Bellis G., Moreno-Mayar J.V., Restrepo B.N., Rojas W., Avendaño-Tamayo E., Bedoya G., Orlando L., Salas A., Helgason A., Gilbert M.T.P., Sikora M., Schroeder H., Dugoujon J.M. (2017). Genome-wide ancestry and demographic history of African-descendant Maroon communities from French Guiana and Suriname. American Journal of Human Genetics 101(5):725-736, doi: 10.1016/j.ajhg.2017.09.021. PMID: 29100086.

Patin E., Lopez M., Grollemund R., Verdu P., Harmant C., Quach H., Laval G., Perry G.H., Barreiro L.B., Froment A., Heyer E., Massougbodji A., Fortes-Lima C., Migot-Nabias F., Bellis G., Dugoujon J.M., Pereira J.B., Fernandes V., Pereira L., van der Veen L., Mouguiama-Daouda P., Bustamante C.D., Hombert J.M., and Quintana-Murci L. (2017). Dispersals and genetic adaptation of Bantu-speaking populations in Africa and North America. Science 356(6337):543-546, doi: 10.1126/science.aal1988. PMID: 28473590.

Fortes-Lima C. (2016). Tracing the genetic origin of African descendants from South America. Publisher: Editions Universitaires Européennes. Saarbrücken, Germany. Scientific Book. ISBN-10: 3639847660. EAN: 9783639847666. Number of pages: 280p.

Fortes-Lima C., Brucato N., Croze M., Bellis G., Schiavinato S., Massougbodji A., Migot-Nabias F., and Dugoujon J.M. (2015). Genetic population study of Y-chromosome markers in Benin and Ivory Coast ethnic groups. Forensic Science International: Genetics 19:232-237, doi:10.1016/j.fsigen.2015.07.021. PMID: 26275614.

Fortes-Lima C., Dugoujon J.M., Hernandez C.L., Reales G., and Calderon R. (2014). Immunoglobulin genes in Andalusia (Spain). Genetic diversity in the Mediterranean space. Comptes Rendus Biologies 337(11):646-656. PMID: 25444709.

Afshan K., Fortes-Lima C., Artigas P., Valero A.M., Qayyum M., Mas-Coma S. (2014). Impact of climate change and man-made irrigation systems on the transmission risk, long-term trend and seasonality of human and animal fascioliasis in Pakistan. Geospatial Health 8(2):317-334. PMID: 24893010.

Reales G., Hernandez C., Dugoujon J.M., Novelletto A., Fortes-Lima C., Rodriguez J.N., and Calderon R. (2014). New insights into the distribution of APOE polymorphism in the Iberian Peninsula. The case of Andalusia (Spain). Annals of Human Biology 41(5):443-452 doi:10.3109/03014460.2013.877966. PMID: 24502694.

Ambrosio B., Novelletto A., Hernandez C., Dugoujon J.M., Fortes-Lima C., Rodriguez J.N., and Calderon R. (2012). Y-STR genetic diversity in autochthonous Andalusians from Huelva and Granada provinces (Spain). Forensic Science International: Genetics 6(2):e66-71. PMID: 21664894.

Ambrosio B., Hernandez C., Novelletto A., Dugoujon J.M., Rodriguez J.N., Cuesta P., Fortes-Lima C., and Calderon R. (2010a). Searching the peopling of the Iberian Peninsula from the genetics of two Andalusian subpopulations: a study based on Y-chromosome haplogroups J and E. Collegium Antropologicum 4:1215-1228. PMID: 21874703.

Ambrosio B., Dugoujon J.M., Hernandez C., De La Fuente D., Gonzalez-Martin A., Fortes-Lima C., Novelletto A., Rodriguez J.N., and Calderon R. (2010b). The Andalusian population from Huelva reveals a high diversification of Y-DNA paternal lineages from haplogroup E: Identifying human male movements within the Mediterranean space. Annals of Human Biology 37:86-107. PMID: 19939195.